Synthra F-Dopa

Production of 6-[18F]fluoro-L-Dopa and a variety of Fluorine-18

A flexible and completely automated synthesis system for routine production of 6-[18F]fluoro-L-Dopa and a variety of Fluorine-18 labelled compounds by electrophilic fluorination. The SynthraView configuration software offers both fully automatic and manual modes of operation of the Synthra F-Dopa module.

The target flow is controlled by a chemically inert flow controller. There are two synthesis reaction vessels allowing trapping of [18F]F2 target gas in separated reaction vessel for optimized reaction yields. Liquid transfer in performed with two build-in dispersers. The module includes a column for an in-process purification step, as well as a built in HPLC for separation. All wetted components are chemically inert, simplifying maintenance and protecting the final product.

Download detailed specification of F-Dopa radiosynthesizer

Examples for electrophilic [18F] compounds

[18F]-Radiotracer Target Application
F-Dopa D2 dopamine receptors Neurodegenerative diseases


Yield 20%, not decay corrected
Synthesis time 43 min
Dimensions 55 cm x 48 cm x 50 cm (w x d x h)
Weight Approx. 45 Kg
Hot Cell (minimum size) 65 cm x 50 cm x 50 cm (w x d x h)