Synthra RNplus

Production of [18F]F-DOPA, [18F]FDG, [18F]FLT, [18F]FHBG, [18F]FDDNP, [18F]MISO, [18F]FAZA and [18F]Fluorocholine

A flexible and completely automated radio synthesis system for routine production of wide variety of Fluorine-18 labeled compounds by nucleophilic substitution with automated sequences for compounds like [18F]F-DOPA, [18F]FDG, [18F]FLT, [18F]FHBG, [18F]FDDNP, [18F]MISO, [18F]FAZA and [18F]Fluorocholine. For any other F-18 labeled customer compound an automated sequence will be generated.

The synthesis unit includes all components needed for preparation, labeling, purification and formulation of Fluorine-18 labeled compounds.

Download detailed specification of RNplus radiosynthesizer

Examples for [18F] compounds

[18F]-Radiotracer Target Application
FLT DNA proliferation Tumor cell proliferation
FDDNP ß-Amyloid protein Alzheimer disease
Flumazenil Benzodiacepine receptor Epileptic foci
FHBG Gene expression Cancer gene therapie
Fluorocholine Choline kinase Prostate I tumor
F-Mizo Hypoxic cell marker Head and neck cancer
F-Dopa D2 dopamine receptors Neurodegenerative diseases
FDG Glucose metabolism Tumor diagnostic


Yields, setup time and synthesis time will vary depending on the biomarker produced.

Yields are dependent on use of proper technique and appropriate reagents.

Dimensions 57 cm x 45 cm x 48 cm (w x d x h)
Weight Approx. 45 Kg
Hot Cell (minimum size) 65 cm x 55 cm x 55 cm (w x d x h)