Synthra RNplus

Production of [18F]F-DOPA, [18F]FDG, [18F]FLT, [18F]FHBG, [18F]FDDNP, [18F]MISO, [18F]FAZA and [18F]Fluorocholine


A flexible and completely automated radio synthesis system for routine production of wide variety of Fluorine-18 labeled compounds by nucleophilic substitution with automated sequences for compounds like [18F]F-DOPA, [18F]FDG, [18F]FLT, [18F]FHBG, [18F]FDDNP, [18F]MISO, [18F]FAZA and [18F]Fluorocholine. For any other F-18 labeled customer compound an automated sequence will be generated.

The synthesis unit includes all components needed for preparation, labeling, purification and formulation of Fluorine-18 labeled compounds.

Download detailed specification of RNplus radiosynthesizer


Examples for [18F] compounds

[18F]-Radiotracer Target Application
FLT DNA proliferation Tumor cell proliferation
FDDNP ß-Amyloid protein Alzheimer disease
Flumazenil Benzodiacepine receptor Epileptic foci
FHBG Gene expression Cancer gene therapie
Fluorocholine Choline kinase Prostate I tumor
F-Mizo Hypoxic cell marker Head and neck cancer
F-Dopa D2 dopamine receptors Neurodegenerative diseases
FDG Glucose metabolism Tumor diagnostic

Specifications:

Yields, setup time and synthesis time will vary depending on the biomarker produced.

Yields are dependent on use of proper technique and appropriate reagents.


Dimensions 57 cm x 45 cm x 48 cm (w x d x h)
Weight Approx. 45 Kg
Hot Cell (minimum size) 65 cm x 55 cm x 55 cm (w x d x h)